The paper discusses some optimization methods for system-object simulation models of processes and systems. In order to increase the efficiency of the system-object analysis of organizational, business and industrial-technological processes by improving the theoretical and instrumental means of optimizing system-object simulation models, the authors formulated some optimization principles that are considered in the article. The paper shows that the optimization of the systemobject model, first of all, is required in order to establish the conformity of the model with system-wide principles and patterns. When constructing simulation models, the authors are guided, inter alia, by the generalized characteristic of the system – a measure of systemicity. This article proposes the optimization of a system-object simulation model using the organizationalmanagerial model of "supervisor-subordinates" in the environment of "UFOModeler". It is proved that the formulated optimization principles allow us to proceed to the development of optimization methods for structural, functional and object parameters of similar simulated systems. Also, it should be noted that the principles of optimization of system-object simulation models considered in the work are not exhaustive.